Sensor-Based CRT Optimization

SonR CRT-D + SonRtip Atrial Lead

The Respond CRT system is a unique combination of a cardiac contractility sensor with an advanced AV & VV delay optimization algorithm.


The SonR sensor consists of a micro accelerometer embedded in the tip of the SonRtip atrial lead.

Correlated with cardiac contractility

The sensor picks up cardiac muscle vibrations that reflect the heart sounds1. SonR signal amplitude is a surrogate for cardiac contractility and correlates with LV dP/dt max. 2


SonR AV & VV Optimization Algorithm

Using the continuous measurements of contractility picked up by the sonR sensor, the SonR algorithm performs weekly optimization of the patient’s AV and VV intervals both at rest and during exercise.

Example of Optimization with SonR

This allows for cardiac resynchronization therapy to be continuously adapted to the individual needs of each patient.


  • 1. Tassin A, Kobeissi A, Vitali L et al. Relationship between amplitude and timing of heart sounds and endocardial acceleration. Pacing Clin Electrophysiol 2009;32(Suppl. 1):S101-104.

  • 2. Bordachar P, Garrigue S, Ritter P et al. Contributions of a hemodyamic sensor embedded in an atrial lead in a porcine model. J Cardiovasc Electrophysiol. 2011 May;22(5):579-83

Hear from the experts

Sensor-based CRT optimization with SonR: experts discuss the tangible benefits of individualized, automatic optimization and the technology behind it.

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The Key Results

Get an overview of the key results from the RESPOND-CRT trial including details on trial design and subgroup analyses.

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